Remember Knull, the god of the symbiotes, whom Donnie Cates and Ryan Stegman rammed down our throats and into our hearts so well he got his own linewide crossover a few years back and just appeared in the third Venom movie?
Well, he’s back, and he’s here to harass the All-New Venom, Mary Jane Watson.
Face it, Jackpot, you just hit the tiger.
Marvel on Monday announced Venom #250, an anniversary issue coming in October from Al Ewing and Terry Dodson that will see Ewing’s All-New Venom series renamed to just Venom, with legacy numbering continuing on from there.
… Y’ever think about how organizing comics is pretty much impossible now?
Anyway, the Knull announcement (Knull knews?) was a highlight of 616 Day, a Marvel celebration born of the fact that Earth-616 is the most important Earth in the Marvel Multiverse. We’re posting this a little late in the day, but we hope you got to celebrate by not thinking about any of those other Earths, even Earth-6160, which is a pretty dang well-written Earth.
Check out the teaser to Venom #250 below, and keep scrolling for Marvel’s press release.

To celebrate 616 Day, Marvel Comics is thrilled to announce that the landmark 250th issue of VENOM hits stands in October and features the return of KNULL, Venom’s greatest enemy!
Written by current All-New Venom scribe Al Ewing and drawn by superstar artist Terry Dodson, VENOM #250 kicks off a major symbiote saga where Knull, the god of symbiotes, seeks revenge on Venom, who is currently bonded to Mary Jane Watson! Debuting in Donny Cates and Ryan Stegman’s seminal run of Venom back in 2018, Knull immediately took a spot amongst Marvel’s most feared and legendary supervillains, going on to headline his own crossover event as the KING IN BLACK and even making his big screen debut in last year’s Venom: The Last Dance. Now, he’s back with a vengeance, and Mary Jane has no idea what’s in store!
The giant-sized celebratory issue will also feature a tale by Eddie Brock: Carnage writer Charles Soule and All-New Venom artist Carlos Gomez set during Eddie Brock’s time as Venom. Plus, following the issue, ALL-NEW VENOM remains VENOM once more, continuing on with the legacy numbering with VENOM #251!
THE RETURN OF KNULL!
Mary Jane Watson is finally in the swing of things as the new Venom host, using their powers in all-new ways to be the hero the symbiote never knew it could be! But as she cleans up the streets of New York, she remains blissfully unaware of the strands of darkness leading off into the darkness of the void. Knull, the creator of all symbiotes, was killed by Eddie Brock. Nothing could bring him back… but Knull rules over nothing. Knull has returned, and word is racing across the stars to the one who took him down before to prepare to do it again. Will Venom be ready?
On Knull’s appeal, Ewing said, “When Donny and Ryan brought Knull into being, they created the first new villain in a while with what I’d call ‘big villain juice.’ He’s visually arresting, you know what he wants in one sentence, you can’t talk him out of it, he’s powerful enough to hold down a crossover… and he was given the wonderful luxury of going away for a while. When a big bad is allowed to lay fallow and drift into memory, what’s remembered is all the things readers liked about them – and that’s when it’s time for a comeback. The final ingredient in a good villain – they may be down, but they’re never out.”
Check out the cover and preorder VENOM #250 at your local comic shop today! For more information, visit Marvel.com.
Dan Grote is the editor and publisher of ComicsXF, having won the site by ritual combat. By day, he’s a newspaper editor, and by night, he’s … also an editor. He co-hosts The ComicsXF Interview Podcast with Matt Lazorwitz. He lives in New Jersey with his wife, two kids and two miniature dachshunds, and his third, fictional son, Peter Paul Winston Wisdom. Follow him @danielpgrote.bsky.social.